The Tissue Modulation Laboratory


Metabolic Tissue Engineering

Using macromolecular crowding technology pioneered in our own lab, we can efficiently produce brown fat tissue from human stem cells. Our aim is to treat obesity and diabetes.

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Tissue-Modulating Materials

We are developing cell-free biomaterial implants that influence cellular action in situ via delivery of small molecules. This challenges the classical paradigm of Tissue Engineering, which has been the use of live cell scaffolds for biomaterials.

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Macromolecular Crowding & Stem Cell Platform

Our longest-standing and most successful biotechnological platform uses large molecules (macromolecules) to "crowd" cell cultures. This speeds up most cellular processes via a phenomenon known as the Excluded Volume Effect (EVE).

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TML works together closely with a wide variety of talented scientific and industrial collaborators.

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